Identifying the Initiation of a New Line of Therapy for Metastatic Lung, Breast, and Colorectal Cancer in Real-World Data: A Scoping Review
Oncology
Other
article
Auteurs : O. Onasanya, S.H. Mahmoudpour, B. Bates, I.M. Shui, G. Liu, E.H. Tan, Y.H. Yang, M. Salas, J. Fadare, D. Bennett, P.L. de M. Drummond, J.Y. Shin, S. Guleria, J. R. Wang, M. Hada, H. Denis, S. Setoguchi, I. Truter, L. C. Lopes, R. Wangia Dixon
Date de publication : 27 April 2026
Objectives
This study aimed to identify and synthesize published algorithms for identifying the initiation of a new line of therapy (LOT) for metastatic lung, breast, and colorectal cancer in real-world data (RWD).
Conclusion
Different algorithms are being used to identify LOT initiation for metastatic cancer. Most algorithms require an incident diagnosis of metastasis before considering subsequent SACT as newly initiated LOT for metastatic cancer. However, definitions of metastasis onset and gap duration to therapy initiation vary.