{"id":6058,"date":"2026-05-13T11:40:05","date_gmt":"2026-05-13T09:40:05","guid":{"rendered":"https:\/\/heva-data.com\/?p=6058"},"modified":"2026-06-04T15:52:41","modified_gmt":"2026-06-04T13:52:41","slug":"stage-m2-f-h-methodologie-pharmacoepidemiologique-real-world-evidence-lyon","status":"publish","type":"post","link":"https:\/\/heva-data.com\/en\/stage-m2-f-h-methodologie-pharmacoepidemiologique-real-world-evidence-lyon\/","title":{"rendered":"STAGE M2 (F\/H) \u2013 M\u00e9thodologie Pharmaco\u00e9pid\u00e9miologique &amp; Real-World Evidence \u2013 Lyon"},"content":{"rendered":"<p>[et_pb_section fb_built=\u00a0\u00bb1&Prime; _builder_version=\u00a0\u00bb4.24.2&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb background_enable_image=\u00a0\u00bboff\u00a0\u00bb custom_margin=\u00a0\u00bb||0px||false|false\u00a0\u00bb custom_padding=\u00a0\u00bb0px||||false|false\u00a0\u00bb locked=\u00a0\u00bboff\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_row column_structure=\u00a0\u00bb3_5,2_5&Prime; make_equal=\u00a0\u00bbon\u00a0\u00bb custom_padding_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb _builder_version=\u00a0\u00bb4.24.2&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb width_tablet=\u00a0\u00bb\u00a0\u00bb width_phone=\u00a0\u00bb90%\u00a0\u00bb width_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_margin_tablet=\u00a0\u00bb\u00a0\u00bb custom_margin_phone=\u00a0\u00bb||0px||false|false\u00a0\u00bb custom_margin_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_padding_tablet=\u00a0\u00bb\u00a0\u00bb custom_padding_phone=\u00a0\u00bb||0px||false|false\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_column type=\u00a0\u00bb3_5&Prime; _builder_version=\u00a0\u00bb4.24.2&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_text _builder_version=\u00a0\u00bb4.27.4&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb text_text_color=\u00a0\u00bbgcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2&Prime; text_font_size=\u00a0\u00bb16px\u00a0\u00bb header_text_align=\u00a0\u00bbcenter\u00a0\u00bb module_alignment=\u00a0\u00bbcenter\u00a0\u00bb custom_padding=\u00a0\u00bb|0px||0px|false|true\u00a0\u00bb locked=\u00a0\u00bboff\u00a0\u00bb global_colors_info=\u00a0\u00bb{%22gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2%22:%91%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22%93}\u00a0\u00bb]<\/p>\n<p style=\"font-weight: 400;\">Heva, filiale de Docaposte et une expertise de La Poste Sant\u00e9 &amp; Autonomie, est un acteur majeur de la valorisation des donn\u00e9es de sant\u00e9 : de la collecte, \u00e0 l\u2019exploitation et la restitution des r\u00e9sultats.<\/p>\n<p style=\"font-weight: 400;\">Elle accompagne les professionnels de l\u2019industrie pharmaceutique, du dispositif m\u00e9dical, les entreprises de biotechnologie ou encore et les institutionnels du secteur de la sant\u00e9 dans la gestion de tous types d\u2019\u00e9tudes sur donn\u00e9es de sant\u00e9.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00a0\u00bb2_5&Prime; _builder_version=\u00a0\u00bb4.24.2&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb background_color=\u00a0\u00bbgcid-c0e66333-91cf-44de-bb84-3ca29293711d\u00a0\u00bb background_enable_color=\u00a0\u00bboff\u00a0\u00bb background_image=\u00a0\u00bbhttps:\/\/heva-data.com\/wp-content\/uploads\/2025\/03\/people-working-in-co-working-office-2025-03-09-17-18-57-utc-1.jpg\u00a0\u00bb custom_padding=\u00a0\u00bb10%||||false|false\u00a0\u00bb custom_padding_tablet=\u00a0\u00bb10%||||false|false\u00a0\u00bb custom_padding_phone=\u00a0\u00bb30%||||false|false\u00a0\u00bb custom_padding_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_css_free_form=\u00a0\u00bbselector{|| border:3px solid white;||}\u00a0\u00bb border_radii=\u00a0\u00bbon|30px|30px|30px|30px\u00a0\u00bb global_colors_info=\u00a0\u00bb{%22gcid-c0e66333-91cf-44de-bb84-3ca29293711d%22:%91%22background_color%22%93,%22gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2%22:%91%22background_color%22%93}\u00a0\u00bb][\/et_pb_column][\/et_pb_row][et_pb_row use_custom_gutter=\u00a0\u00bbon\u00a0\u00bb gutter_width=\u00a0\u00bb2&Prime; 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_module_preset=\u00a0\u00bbdefault\u00a0\u00bb text_text_color=\u00a0\u00bbgcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2&Prime; text_font_size=\u00a0\u00bb16px\u00a0\u00bb header_text_align=\u00a0\u00bbcenter\u00a0\u00bb text_orientation=\u00a0\u00bbcenter\u00a0\u00bb module_alignment=\u00a0\u00bbcenter\u00a0\u00bb custom_padding=\u00a0\u00bb|0px||0px|false|true\u00a0\u00bb locked=\u00a0\u00bboff\u00a0\u00bb global_colors_info=\u00a0\u00bb{%22gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2%22:%91%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22%93}\u00a0\u00bb]Nous cherchons :[\/et_pb_text][et_pb_text _builder_version=\u00a0\u00bb4.27.4&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb text_text_color=\u00a0\u00bbgcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2&Prime; text_font_size=\u00a0\u00bb24px\u00a0\u00bb header_2_font=\u00a0\u00bb|700|||||||\u00a0\u00bb header_2_text_align=\u00a0\u00bbcenter\u00a0\u00bb header_2_text_color=\u00a0\u00bbgcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2&Prime; header_2_font_size=\u00a0\u00bb33px\u00a0\u00bb header_3_font=\u00a0\u00bb|700|||||||\u00a0\u00bb header_3_text_align=\u00a0\u00bbcenter\u00a0\u00bb header_3_text_color=\u00a0\u00bbgcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2&Prime; header_3_font_size=\u00a0\u00bb24px\u00a0\u00bb text_orientation=\u00a0\u00bbcenter\u00a0\u00bb custom_margin=\u00a0\u00bb0px||0px||false|false\u00a0\u00bb custom_padding=\u00a0\u00bb0px|0px|0px|0px|false|true\u00a0\u00bb custom_css_free_form=\u00a0\u00bbselector span{|| color:#1aa6a6;||}\u00a0\u00bb locked=\u00a0\u00bboff\u00a0\u00bb global_colors_info=\u00a0\u00bb{%22gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2%22:%91%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22%93}\u00a0\u00bb]<strong>STAGE M2 (F\/H) \u2013 M\u00e9thodologie Pharmaco\u00e9pid\u00e9miologique &amp; Real-World Evidence \u2013 Lyon<\/strong>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00a0\u00bb1&Prime; custom_padding_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb module_class=\u00a0\u00bbparallax\u00a0\u00bb _builder_version=\u00a0\u00bb4.24.2&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb background_color=\u00a0\u00bbgcid-f237d54e-6be2-4a68-9ae3-f3ddd196256e\u00a0\u00bb background_image=\u00a0\u00bbhttps:\/\/heva-data.com\/wp-content\/uploads\/2025\/04\/technology-software-programming-develop-idea-peopl-2025-03-15-04-27-40-utc-1.jpg\u00a0\u00bb background_blend=\u00a0\u00bbhard-light\u00a0\u00bb module_alignment=\u00a0\u00bbcenter\u00a0\u00bb min_height=\u00a0\u00bb750px\u00a0\u00bb custom_padding=\u00a0\u00bb||0px||false|false\u00a0\u00bb custom_padding_tablet=\u00a0\u00bb||0px||false|false\u00a0\u00bb custom_padding_phone=\u00a0\u00bb0px||0px||false|false\u00a0\u00bb custom_css_free_form=\u00a0\u00bbselector{|| overflow:hidden;|| width:calc(100% &#8211; 140px);|| left:70px;||} ||\/* Adaptation pour les \u00e9crans plus petits (mobile) *\/||@media screen and (max-width: 768px) {|| selector {|| width: calc(90%); \/* R\u00e9duction de la marge pour s&rsquo;adapter aux petits \u00e9crans *\/|| left: 5%; \/* Ajustement du d\u00e9calage lat\u00e9ral *\/|| }||}\u00a0\u00bb border_radii=\u00a0\u00bbon|20px|20px|20px|20px\u00a0\u00bb locked=\u00a0\u00bboff\u00a0\u00bb global_colors_info=\u00a0\u00bb{%22gcid-f237d54e-6be2-4a68-9ae3-f3ddd196256e%22:%91%22background_color%22%93}\u00a0\u00bb][et_pb_row column_structure=\u00a0\u00bb1_2,1_2&Prime; make_equal=\u00a0\u00bbon\u00a0\u00bb custom_padding_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb _builder_version=\u00a0\u00bb4.24.2&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb width_tablet=\u00a0\u00bb\u00a0\u00bb width_phone=\u00a0\u00bb90%\u00a0\u00bb width_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb max_width=\u00a0\u00bb90%\u00a0\u00bb custom_margin=\u00a0\u00bb6vw||6vw||false|false\u00a0\u00bb custom_padding_tablet=\u00a0\u00bb\u00a0\u00bb custom_padding_phone=\u00a0\u00bb0px||||false|false\u00a0\u00bb custom_css_free_form=\u00a0\u00bbselector{|| z-index:500;||}\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_column type=\u00a0\u00bb1_2&Prime; _builder_version=\u00a0\u00bb4.24.2&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb custom_padding=\u00a0\u00bb50px|50px|50px|50px|false|false\u00a0\u00bb custom_padding_tablet=\u00a0\u00bb50px|50px|50px|50px|false|false\u00a0\u00bb custom_padding_phone=\u00a0\u00bb30px|10px|30px|10px|false|false\u00a0\u00bb custom_padding_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_css_free_form=\u00a0\u00bbselector{|| position: relative;|| z-index: 1; \/* S&rsquo;assurer que le texte est au-dessus *\/|| background-color: rgba(221, 242, 242, 0.95); \/* Turquoise tram\u00e9 \u00e0 15% *\/|| opacity: 1; \/* Effet de transparence \u00e0 95% *\/|| color: #000; \/* Couleur du texte, \u00e0 ajuster si n\u00e9cessaire *\/|| backdrop-filter: blur(5px);|| -webkit-backdrop-filter: blur(5px);||}\u00a0\u00bb border_radii=\u00a0\u00bbon|30px|30px|30px|30px\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_text _builder_version=\u00a0\u00bb4.27.4&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb text_text_color=\u00a0\u00bbgcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2&Prime; text_font_size=\u00a0\u00bb16px\u00a0\u00bb custom_padding=\u00a0\u00bb|26px||0px|false|false\u00a0\u00bb locked=\u00a0\u00bboff\u00a0\u00bb global_colors_info=\u00a0\u00bb{%22gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2%22:%91%22text_text_color%22%93}\u00a0\u00bb]<\/p>\n<p><strong>Titre :<\/strong> Robustesse des \u00e9tudes comparatives en vie r\u00e9elle : cartographie des t\u00e9moins n\u00e9gatifs (<em>Negative Control Outcomes<\/em>) et calibration empirique dans le SNDS<\/p>\n<p><strong>Dur\u00e9e :<\/strong> 6 mois | <strong>Lieu :<\/strong> Lyon, France | <strong>D\u00e9marrage :<\/strong> Janvier 2027<\/p>\n<ol>\n<li><strong> Contexte scientifique<\/strong><\/li>\n<\/ol>\n<p>Les \u00e9tudes observationnelles d&rsquo;efficacit\u00e9 et de s\u00e9curit\u00e9 comparatives constituent aujourd&rsquo;hui le socle de la production de preuves en vie r\u00e9elle (<em>Real-World Evidence<\/em>, RWE), qu&rsquo;il s&rsquo;agisse de d\u00e9cisions de remboursement, d&rsquo;\u00e9valuations post-inscription ou d&rsquo;\u00e9tudes de pharmacovigilance active. Malgr\u00e9 le recours \u00e0 des m\u00e9thodes d&rsquo;ajustement avanc\u00e9es \u2014 scores de propension, pond\u00e9ration par l&rsquo;inverse de la probabilit\u00e9 de traitement (IPTW), appariement \u2014 un biais r\u00e9siduel syst\u00e9matique persiste dans la quasi-totalit\u00e9 des \u00e9tudes observationnelles, en raison notamment des facteurs de confusion non mesur\u00e9s : biais d&rsquo;indication, <em>healthy user bias<\/em>, fragilit\u00e9 non cod\u00e9e dans les bases m\u00e9dico-administratives.<\/p>\n<p>L&rsquo;approche par calibration empirique (<em>Empirical Calibration<\/em>), formalis\u00e9e et popularis\u00e9e par le consortium OHDSI dans le cadre du programme LEGEND, propose une r\u00e9ponse quantitative \u00e0 ce d\u00e9fi. Le principe consiste \u00e0 estimer la distribution empirique du biais r\u00e9siduel en mesurant l&rsquo;effet apparent du traitement sur une s\u00e9rie d&rsquo;\u00e9v\u00e9nements t\u00e9moins n\u00e9gatifs (<em>Negative Control Outcomes<\/em>, NCOs) \u2014 des \u00e9v\u00e9nements cliniques pour lesquels toute relation causale avec le traitement est biologiquement non plausible. Si un signal appara\u00eet sur ces t\u00e9moins, il refl\u00e8te n\u00e9cessairement un biais syst\u00e9matique que l&rsquo;on peut mod\u00e9liser et corriger. Cette distribution de l&rsquo;hypoth\u00e8se nulle empirique est ensuite utilis\u00e9e pour recalibrer l&rsquo;estimateur et les intervalles de confiance de l&rsquo;outcome d&rsquo;int\u00e9r\u00eat.<\/p>\n<p>Bien que la m\u00e9thode soit d\u00e9sormais reconnue comme une bonne pratique m\u00e9thodologique dans les grandes \u00e9tudes de pharmaco\u00e9pid\u00e9miologie internationale, son d\u00e9ploiement en routine sur des donn\u00e9es fran\u00e7aises reste tr\u00e8s limit\u00e9. La principale raison tient \u00e0 l&rsquo;absence de cartographie structur\u00e9e des NCOs adapt\u00e9s aux sp\u00e9cificit\u00e9s du Syst\u00e8me National des Donn\u00e9es de Sant\u00e9 (SNDS) \u2014 codage CIM-10, CCAM, remboursements DCIR \u2014 et aux diff\u00e9rentes aires th\u00e9rapeutiques.<\/p>\n<ol start=\"2\">\n<li><strong> Objectifs du stage<\/strong><\/li>\n<\/ol>\n<p>Le stage s&rsquo;articule autour de deux axes compl\u00e9mentaires.<\/p>\n<p><strong>Axe m\u00e9thodologique<\/strong> :<\/p>\n<ul>\n<li>R\u00e9aliser une revue de port\u00e9e (<em>scoping review<\/em>) des NCOs utilis\u00e9s dans la litt\u00e9rature pharmaco\u00e9pid\u00e9miologique,<\/li>\n<li>Stratifi\u00e9e par domaine th\u00e9rapeutique (oncologie, cardiologie, diab\u00e9tologie, infectiologie) et par population cible (sujet \u00e2g\u00e9, femme enceinte, patient immunod\u00e9prim\u00e9).<\/li>\n<li>Cette cartographie aboutira \u00e0 une matrice op\u00e9rationnelle croisant candidats NCOs et faisabilit\u00e9 de leur transposition en algorithmes SNDS.<\/li>\n<\/ul>\n<p><strong>Axe appliqu\u00e9<\/strong> :<\/p>\n<p>Mettre en \u0153uvre une preuve de concept (<em>proof of concept<\/em>) compl\u00e8te de calibration empirique sur un cas d&rsquo;usage r\u00e9el \u00e0 partir du SNDS, en allant de la construction de cohorte jusqu&rsquo;\u00e0 la recalibration de l&rsquo;estimateur principal.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00a0\u00bb1_2&Prime; _builder_version=\u00a0\u00bb4.24.2&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb custom_padding=\u00a0\u00bb50px|50px|50px|50px|false|false\u00a0\u00bb custom_padding_tablet=\u00a0\u00bb50px|50px|50px|50px|false|false\u00a0\u00bb custom_padding_phone=\u00a0\u00bb30px|10px|30px|10px|false|false\u00a0\u00bb custom_padding_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_css_free_form=\u00a0\u00bbselector{|| position: relative;|| z-index: 1; \/* S&rsquo;assurer que le texte est au-dessus *\/|| background-color: rgba(221, 242, 242, 0.95); \/* Turquoise tram\u00e9 \u00e0 15% *\/|| opacity: 1; \/* Effet de transparence \u00e0 95% *\/|| color: #000; \/* Couleur du texte, \u00e0 ajuster si n\u00e9cessaire *\/|| backdrop-filter: blur(5px);|| -webkit-backdrop-filter: blur(5px);||}\u00a0\u00bb border_radii=\u00a0\u00bbon|30px|30px|30px|30px\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_text _builder_version=\u00a0\u00bb4.27.4&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb text_text_color=\u00a0\u00bbgcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2&Prime; text_font_size=\u00a0\u00bb16px\u00a0\u00bb custom_padding=\u00a0\u00bb|26px||0px|false|false\u00a0\u00bb locked=\u00a0\u00bboff\u00a0\u00bb global_colors_info=\u00a0\u00bb{%22gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2%22:%91%22text_text_color%22%93}\u00a0\u00bb]<\/p>\n<ol start=\"3\">\n<li><strong> Missions<\/strong><\/li>\n<\/ol>\n<p><strong>Phase 1 \u2014 Revue et cartographie des NCOs (mois 1\u20132)<\/strong><\/p>\n<p>Le stagiaire conduira une revue structur\u00e9e de la litt\u00e9rature portant sur les pratiques de s\u00e9lection des NCOs dans les publications pharmaco\u00e9pid\u00e9miologiques majeures, en distinguant les approches de <em>manual curation<\/em> (s\u00e9lection experte a priori) et les approches <em>data-driven<\/em> (extraction algorithmique \u00e0 partir d&rsquo;ontologies m\u00e9dicales ou de bases de pharmacovigilance).<\/p>\n<p>Le livrable principal de cette phase est une matrice NCOs \u00d7 domaines th\u00e9rapeutiques, incluant pour chaque candidat NCO : le niveau de preuve de l&rsquo;absence d&rsquo;effet biologique, la faisabilit\u00e9 de codage dans le SNDS (codes CIM-10 \/ CCAM identifi\u00e9s), la sensibilit\u00e9 attendue dans les donn\u00e9es de remboursement, et les limites potentielles (sous-codage, variabilit\u00e9 inter-\u00e9tablissements). Ce document est con\u00e7u pour \u00eatre r\u00e9utilisable dans les futurs protocoles d&rsquo;\u00e9tude et opposable aux autorit\u00e9s d&rsquo;\u00e9valuation (HAS, EMA).<\/p>\n<p><strong>Phase 2 \u2014 Design du cas d&rsquo;usage et extraction de donn\u00e9es (mois 3)<\/strong><\/p>\n<p>Un cas d&rsquo;usage sera d\u00e9fini en concertation avec l&rsquo;\u00e9quipe encadrante, en s&rsquo;appuyant sur des \u00e9tudes r\u00e9centes du bureau d\u2019\u00e9tude en cours ou achev\u00e9es pour lesquelles une r\u00e9analyse m\u00e9thodologique apporte une plus-value scientifique. La question de recherche sera formalis\u00e9e en format PICO et le protocole d&rsquo;\u00e9tude adapt\u00e9 aux contraintes de l&rsquo;ESND\/SNDS (effectifs, dur\u00e9e de suivi disponible, couverture des variables d&rsquo;ajustement). La cohorte sera d\u00e9j\u00e0 construite \u00e0 partir des tables DCIR et PMSI MCO. Il sera n\u00e9cessaire d\u2019ajouter les variables n\u00e9cessaires \u00e0 l\u2019analyse propos\u00e9e dans le stage.<\/p>\n<p><strong>Phase 3 \u2014 Analyse statistique et calibration (mois 4\u20135)<\/strong><\/p>\n<p>Les facteurs de confusion mesur\u00e9s seront ajust\u00e9s par des m\u00e9thodes \u00e0 base de score de propension. L\u2019outcome principal ainsi que le panel de NCOs s\u00e9lectionn\u00e9s en Phase 1 seront estim\u00e9s \u00e0 l\u2019aide mod\u00e8les de r\u00e9gressions adapt\u00e9s, afin de mod\u00e9liser la distribution empirique de l&rsquo;hypoth\u00e8se nulle et de recalibrer les estimateurs de l&rsquo;\u00e9tude.<\/p>\n<p><strong>Phase 4 \u2014 Synth\u00e8se et valorisation (mois 6)<\/strong><\/p>\n<p>Le stagiaire r\u00e9digera son m\u00e9moire (structure IMRaD) et produira un script R \/ python document\u00e9, couvrant l&rsquo;ensemble de la cha\u00eene analytique, destin\u00e9 \u00e0 \u00eatre int\u00e9gr\u00e9 aux workflows standard du bureau. Un abstract\/poster sera pr\u00e9par\u00e9 en vue d&rsquo;une soumission \u00e0 un congr\u00e8s de pharmaco\u00e9pid\u00e9miologie (ISPE, DSVR ou EMOIS selon le calendrier).<\/p>\n<ol start=\"4\">\n<li><strong> Profil recherch\u00e9<\/strong><\/li>\n<\/ol>\n<p>Le stage s&rsquo;adresse \u00e0 un(e) \u00e9tudiant(e) en deuxi\u00e8me ann\u00e9e de Master en Biostatistiques, \u00c9pid\u00e9miologie ou Sant\u00e9 Publique, avec une app\u00e9tence marqu\u00e9e pour les questions de validit\u00e9 interne et d&rsquo;inf\u00e9rence causale en \u00e9tudes observationnelles.<\/p>\n<p>Une exp\u00e9rience avec les bases de donn\u00e9es de sant\u00e9 fran\u00e7aises (SNDS\/EGB\/ESND) et une bonne ma\u00eetrise de SAS \/ R \/ Python constitue un atout significatif. La capacit\u00e9 \u00e0 lire et synth\u00e9tiser la litt\u00e9rature m\u00e9thodologique en anglais est attendue.<\/p>\n<p>Au-del\u00e0 des comp\u00e9tences techniques, le profil recherch\u00e9 est celui d&rsquo;un esprit rigoureux et critique, capable de questionner ses propres r\u00e9sultats et d&rsquo;identifier les sources potentielles d&rsquo;art\u00e9fact avant d&rsquo;en tirer des conclusions. Une certaine autonomie de recherche est attendue d\u00e8s la Phase 1, tout en s&rsquo;inscrivant dans un fonctionnement d&rsquo;\u00e9quipe.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\u00a0\u00bb4.24.2&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb background_enable_color=\u00a0\u00bboff\u00a0\u00bb background_image=\u00a0\u00bbhttps:\/\/heva-data.com\/wp-content\/uploads\/2025\/03\/line_green3_left.png\u00a0\u00bb background_size=\u00a0\u00bbcustom\u00a0\u00bb background_image_height=\u00a0\u00bb600px\u00a0\u00bb background_position=\u00a0\u00bbtop_left\u00a0\u00bb background_vertical_offset=\u00a0\u00bb0%\u00a0\u00bb custom_margin=\u00a0\u00bb-390px|0px|0px||false|false\u00a0\u00bb custom_padding=\u00a0\u00bb|0px|0px|0px|false|false\u00a0\u00bb custom_css_free_form=\u00a0\u00bbselector{|| width:740px;|| height:390px;|| top:auto;bottom:-120px;|| left:auto;right:-15px;|| z-index:0;||}\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_column type=\u00a0\u00bb4_4&Prime; _builder_version=\u00a0\u00bb4.24.2&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00a0\u00bb1&Prime; _builder_version=\u00a0\u00bb4.24.2&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_row _builder_version=\u00a0\u00bb4.24.2&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_column type=\u00a0\u00bb4_4&Prime; _builder_version=\u00a0\u00bb4.24.2&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_text _builder_version=\u00a0\u00bb4.27.4&Prime; _module_preset=\u00a0\u00bbdefault\u00a0\u00bb text_text_color=\u00a0\u00bbgcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2&Prime; text_font_size=\u00a0\u00bb16px\u00a0\u00bb link_text_color=\u00a0\u00bbgcid-4aeecbf4-ad8a-42cd-966b-141db4843095&Prime; custom_padding=\u00a0\u00bb|26px||0px|false|false\u00a0\u00bb locked=\u00a0\u00bboff\u00a0\u00bb global_colors_info=\u00a0\u00bb{%22gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2%22:%91%22text_text_color%22%93,%22gcid-4aeecbf4-ad8a-42cd-966b-141db4843095%22:%91%22link_text_color%22%93}\u00a0\u00bb]<\/p>\n<p style=\"font-weight: 400;\"><strong>Vos conditions de travail :<\/strong><\/p>\n<p>Le stagiaire sera int\u00e9gr\u00e9 \u00e0 l&rsquo;\u00e9quipe d&rsquo;\u00e9pid\u00e9miologie et b\u00e9n\u00e9ficiera d&rsquo;un encadrement direct par un pharmaco\u00e9pid\u00e9miologiste (Benjamin GRENIER). Les analyses s&rsquo;effectueront sur un environnement s\u00e9curis\u00e9 conforme aux exigences du RGPD et aux r\u00e9f\u00e9rentiels de s\u00e9curit\u00e9 de la CNIL (donn\u00e9es pseudonymis\u00e9es). La gratification est conforme \u00e0 la r\u00e9glementation en vigueur.<\/p>\n<p>Merci d&rsquo;envoyer votre dossier de candidature (CV+ lettre de motivation) \u00e0 <a href=\"mailto:aurelie.schmidt@heva-data.com\">benjamin.grenier@heva-data.com<\/a>.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Heva, filiale de Docaposte et une expertise de La Poste Sant\u00e9 &amp; Autonomie, est un acteur majeur de la valorisation des donn\u00e9es de sant\u00e9 : de la collecte, \u00e0 l\u2019exploitation et la restitution des r\u00e9sultats. Elle accompagne les professionnels de l\u2019industrie pharmaceutique, du dispositif m\u00e9dical, les entreprises de biotechnologie ou encore et les institutionnels du [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"[et_pb_section fb_built=\"1\" _builder_version=\"4.24.2\" _module_preset=\"default\" background_enable_image=\"off\" custom_margin=\"||0px||false|false\" custom_padding=\"0px||||false|false\" locked=\"off\" global_colors_info=\"{}\"][et_pb_row column_structure=\"3_5,2_5\" make_equal=\"on\" custom_padding_last_edited=\"on|phone\" _builder_version=\"4.24.2\" _module_preset=\"default\" width_tablet=\"\" width_phone=\"90%\" width_last_edited=\"on|phone\" custom_margin_tablet=\"\" custom_margin_phone=\"||0px||false|false\" custom_margin_last_edited=\"on|phone\" custom_padding_tablet=\"\" custom_padding_phone=\"||0px||false|false\" global_colors_info=\"{}\"][et_pb_column type=\"3_5\" _builder_version=\"4.24.2\" _module_preset=\"default\" global_colors_info=\"{}\"][et_pb_text _builder_version=\"4.27.4\" _module_preset=\"default\" text_text_color=\"gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2\" text_font_size=\"16px\" header_text_align=\"center\" module_alignment=\"center\" custom_padding=\"|0px||0px|false|true\" locked=\"off\" global_colors_info=\"{%22gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2%22:%91%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22%93}\"]\n<p style=\"font-weight: 400;\">Heva, filiale de Docaposte et une expertise de La Poste Sant\u00e9 &amp; Autonomie, est un acteur majeur de la valorisation des donn\u00e9es de sant\u00e9 : de la collecte, \u00e0 l\u2019exploitation et la restitution des r\u00e9sultats.<\/p>\n<p style=\"font-weight: 400;\">Elle accompagne les professionnels de l\u2019industrie pharmaceutique, du dispositif m\u00e9dical, les entreprises de biotechnologie ou encore et les institutionnels du secteur de la sant\u00e9 dans la gestion de tous types d\u2019\u00e9tudes sur donn\u00e9es de sant\u00e9.<\/p>\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\"2_5\" _builder_version=\"4.24.2\" _module_preset=\"default\" background_color=\"gcid-c0e66333-91cf-44de-bb84-3ca29293711d\" background_enable_color=\"off\" background_image=\"https:\/\/heva-data.com\/wp-content\/uploads\/2025\/03\/people-working-in-co-working-office-2025-03-09-17-18-57-utc-1.jpg\" custom_padding=\"10%||||false|false\" custom_padding_tablet=\"10%||||false|false\" custom_padding_phone=\"30%||||false|false\" custom_padding_last_edited=\"on|phone\" custom_css_free_form=\"selector{|| border:3px solid white;||}\" border_radii=\"on|30px|30px|30px|30px\" global_colors_info=\"{%22gcid-c0e66333-91cf-44de-bb84-3ca29293711d%22:%91%22background_color%22%93,%22gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2%22:%91%22background_color%22%93}\"][\/et_pb_column][\/et_pb_row][et_pb_row use_custom_gutter=\"on\" gutter_width=\"2\" make_equal=\"on\" _builder_version=\"4.24.2\" _module_preset=\"default\" custom_margin=\"25px||25px||true|false\" custom_padding=\"20px|20px|20px|20px|true|true\" custom_css_free_form=\"selector{|| z-index:500;|| position: relative;|| z-index: 1; \/* S'assurer que le texte est au-dessus *\/|| background-color: rgba(221, 242, 242, 0.95); \/* Turquoise tram\u00e9 \u00e0 15% *\/|| opacity:1; \/* Effet de transparence \u00e0 95% *\/|| color: #000; \/* Couleur du texte, \u00e0 ajuster si n\u00e9cessaire *\/|| backdrop-filter: blur(5px);|| \/* Pr\u00e9fixe pour la compatibilit\u00e9 avec Safari *\/|| -webkit-backdrop-filter: blur(5px);||}\" border_radii=\"on|30px|30px|30px|30px\" global_colors_info=\"{}\"][et_pb_column type=\"4_4\" _builder_version=\"4.24.2\" _module_preset=\"default\" custom_padding=\"20px|10px|10px|10px|false|true\" border_radii=\"on|20px|20px|20px|20px\" global_colors_info=\"{}\"][et_pb_text _builder_version=\"4.27.4\" _module_preset=\"default\" text_text_color=\"gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2\" text_font_size=\"16px\" header_text_align=\"center\" text_orientation=\"center\" module_alignment=\"center\" custom_padding=\"|0px||0px|false|true\" locked=\"off\" global_colors_info=\"{%22gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2%22:%91%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22,%22text_text_color%22%93}\"]\n\nNous cherchons :\n\n[\/et_pb_text][et_pb_text _builder_version=\"4.27.4\" _module_preset=\"default\" text_text_color=\"gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2\" text_font_size=\"24px\" header_2_font=\"|700|||||||\" header_2_text_align=\"center\" header_2_text_color=\"gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2\" header_2_font_size=\"33px\" header_3_font=\"|700|||||||\" header_3_text_align=\"center\" header_3_text_color=\"gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2\" header_3_font_size=\"24px\" text_orientation=\"center\" custom_margin=\"0px||0px||false|false\" custom_padding=\"0px|0px|0px|0px|false|true\" custom_css_free_form=\"selector span{|| color:#1aa6a6;||}\" locked=\"off\" global_colors_info=\"{%22gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2%22:%91%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22,%22text_text_color%22,%22header_2_text_color%22,%22header_3_text_color%22%93}\"]\n\n<strong>STAGE M2 (F\/H) \u2013 M\u00e9thodologie Pharmaco\u00e9pid\u00e9miologique &amp; Real-World Evidence \u2013 Lyon<\/strong>\n\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" custom_padding_last_edited=\"on|phone\" module_class=\"parallax\" _builder_version=\"4.24.2\" _module_preset=\"default\" background_color=\"gcid-f237d54e-6be2-4a68-9ae3-f3ddd196256e\" background_image=\"https:\/\/heva-data.com\/wp-content\/uploads\/2025\/04\/technology-software-programming-develop-idea-peopl-2025-03-15-04-27-40-utc-1.jpg\" background_blend=\"hard-light\" module_alignment=\"center\" min_height=\"750px\" custom_padding=\"||0px||false|false\" custom_padding_tablet=\"||0px||false|false\" custom_padding_phone=\"0px||0px||false|false\" custom_css_free_form=\"selector{|| overflow:hidden;|| width:calc(100% - 140px);|| left:70px;||} ||\/* Adaptation pour les \u00e9crans plus petits (mobile) *\/||@media screen and (max-width: 768px) {|| selector {|| width: calc(90%); \/* R\u00e9duction de la marge pour s'adapter aux petits \u00e9crans *\/|| left: 5%; \/* Ajustement du d\u00e9calage lat\u00e9ral *\/|| }||}\" border_radii=\"on|20px|20px|20px|20px\" locked=\"off\" global_colors_info=\"{%22gcid-f237d54e-6be2-4a68-9ae3-f3ddd196256e%22:%91%22background_color%22%93}\"][et_pb_row column_structure=\"1_2,1_2\" make_equal=\"on\" custom_padding_last_edited=\"on|phone\" _builder_version=\"4.24.2\" _module_preset=\"default\" width_tablet=\"\" width_phone=\"90%\" width_last_edited=\"on|phone\" max_width=\"90%\" custom_margin=\"6vw||6vw||false|false\" custom_padding_tablet=\"\" custom_padding_phone=\"0px||||false|false\" custom_css_free_form=\"selector{|| z-index:500;||}\" global_colors_info=\"{}\"][et_pb_column type=\"1_2\" _builder_version=\"4.24.2\" _module_preset=\"default\" custom_padding=\"50px|50px|50px|50px|false|false\" custom_padding_tablet=\"50px|50px|50px|50px|false|false\" custom_padding_phone=\"30px|10px|30px|10px|false|false\" custom_padding_last_edited=\"on|phone\" custom_css_free_form=\"selector{|| position: relative;|| z-index: 1; \/* S'assurer que le texte est au-dessus *\/|| background-color: rgba(221, 242, 242, 0.95); \/* Turquoise tram\u00e9 \u00e0 15% *\/|| opacity: 1; \/* Effet de transparence \u00e0 95% *\/|| color: #000; \/* Couleur du texte, \u00e0 ajuster si n\u00e9cessaire *\/|| backdrop-filter: blur(5px);|| -webkit-backdrop-filter: blur(5px);||}\" border_radii=\"on|30px|30px|30px|30px\" global_colors_info=\"{}\"][et_pb_text _builder_version=\"4.27.4\" _module_preset=\"default\" text_text_color=\"gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2\" text_font_size=\"16px\" custom_padding=\"|26px||0px|false|false\" locked=\"off\" global_colors_info=\"{%22gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2%22:%91%22text_text_color%22%93}\"]\n\n<b>Votre profil<\/b>\n\n<strong>Formation\u00a0: <\/strong>\n<ul>\n \t<li>Formation scientifique initiale\u00a0: m\u00e9decin, pharmacien, ing\u00e9nieur, \u00e9conomie de sant\u00e9<\/li>\n \t<li>Exp\u00e9rience d\u2019au moins 3 ans en bureau d\u2019\u00e9tudes\/laboratoire de recherche sp\u00e9cialis\u00e9 dans les \u00e9tudes RWE et\/ou en d\u00e9partements Market Access, HEOR, Affaires M\u00e9dicales au sein des industries de sant\u00e9 (Pharmacie\/Dispositifs m\u00e9dicaux)<\/li>\n<\/ul>\n<strong>Comp\u00e9tences requises : <\/strong>\n<ul>\n \t<li>Connaissances approfondies du syst\u00e8me de sant\u00e9 fran\u00e7ais (Minist\u00e8re de la Sant\u00e9, HAS) et de l\u2019acc\u00e8s au march\u00e9 des produits de sant\u00e9<\/li>\n \t<li>Connaissance des bases de donn\u00e9es du SNDS, du cadre r\u00e9glementaire de leur recueil, et des possibilit\u00e9s techniques de leur exploitation<\/li>\n \t<li>Connaissance du financement des \u00e9tablissements de sant\u00e9 \/ bonnes pratiques en \u00e9conomie de la sant\u00e9 serait un plus<\/li>\n \t<li>Bonne capacit\u00e9 d\u2019int\u00e9gration pour travailler au sein d\u2019une \u00e9quipe multidisciplinaire<\/li>\n \t<li>Bonne capacit\u00e9 d\u2019organisation pour g\u00e9rer plusieurs projets en parall\u00e8le<\/li>\n \t<li>Ma\u00eetrise de l'anglais (r\u00e9daction des propositions, \u00e9changes avec les clients, boards scientifiques\u2026)<\/li>\n<\/ul>\n<div class=\"conclusion\"><\/div>\n<div class=\"conclusion\">\n\n<strong>Lieu du poste<\/strong>\u00a0: Poste bas\u00e9 \u00e0 Lyon\n<strong>Type d'emploi<\/strong>\u00a0: CDI\n\n<\/div>\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_2\" _builder_version=\"4.24.2\" _module_preset=\"default\" custom_padding=\"50px|50px|50px|50px|false|false\" custom_padding_tablet=\"50px|50px|50px|50px|false|false\" custom_padding_phone=\"30px|10px|30px|10px|false|false\" custom_padding_last_edited=\"on|phone\" custom_css_free_form=\"selector{|| position: relative;|| z-index: 1; \/* S'assurer que le texte est au-dessus *\/|| background-color: rgba(221, 242, 242, 0.95); \/* Turquoise tram\u00e9 \u00e0 15% *\/|| opacity: 1; \/* Effet de transparence \u00e0 95% *\/|| color: #000; \/* Couleur du texte, \u00e0 ajuster si n\u00e9cessaire *\/|| backdrop-filter: blur(5px);|| -webkit-backdrop-filter: blur(5px);||}\" border_radii=\"on|30px|30px|30px|30px\" global_colors_info=\"{}\"][et_pb_text _builder_version=\"4.27.4\" _module_preset=\"default\" text_text_color=\"gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2\" text_font_size=\"16px\" custom_padding=\"|26px||0px|false|false\" locked=\"off\" global_colors_info=\"{%22gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2%22:%91%22text_text_color%22%93}\"]\n\n<b>Vos missions<\/b>\n\nAu sein du P\u00f4le Consulting \u2013 Chefferie de projet (10 collaborateurs), en liaison avec les autres chefs de projet et les \u00e9quipes techniques et scientifiques (\u00c9pid\u00e9miologie, Data Management, Statistiques \/ Data Science, Op\u00e9rations Cliniques, Design et D\u00e9veloppement IT), vous avez la charge\u00a0d\u2019accompagner nos clients dans la conception et la r\u00e9alisation d'\u00e9tudes telles que\u00a0:\n<ul>\n \t<li>Etudes r\u00e9trospectives men\u00e9es \u00e0 partir de la base du SNDS, de registres ou de chart review<\/li>\n \t<li>Etudes prospectives sur donn\u00e9es primaires<\/li>\n \t<li>Etudes Acc\u00e8s Pr\u00e9coce<\/li>\n \t<li>Etudes cha\u00een\u00e9es (donn\u00e9es primaires \/ SNDS)<\/li>\n<\/ul>\nLes missions couvriront notamment\u00a0:\n<ul>\n \t<li>R\u00e9ponses aux demandes client\n<ul>\n \t<li>Prise en compte de la probl\u00e9matique client<\/li>\n \t<li>R\u00e9alisation et gestion de la proposition commerciale<\/li>\n<\/ul>\n<\/li>\n \t<li>Gestion des \u00e9tudes\n<ul>\n \t<li>Organisation du lancement des \u00e9tudes, notamment des soumissions r\u00e8glementaires<\/li>\n \t<li>Participer aux \u00e9changes avec les clients et les autorit\u00e9s r\u00e9glementaires (HDH, CNIL, ANSM, HAS\u2026)<\/li>\n \t<li>Animation des boards scientifiques associant les clients et les experts impliqu\u00e9s sur le projet<\/li>\n \t<li>Suivi avec les \u00e9quipes internes du bon d\u00e9roulement des \u00e9tudes (qualit\u00e9, respect des process et des d\u00e9lais\u2026)<\/li>\n \t<li>Gestion de la restitution des r\u00e9sultats des \u00e9tudes aupr\u00e8s des clients (r\u00e9unions de pr\u00e9sentation\/discussion)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\"4.24.2\" _module_preset=\"default\" background_enable_color=\"off\" background_image=\"https:\/\/heva-data.com\/wp-content\/uploads\/2025\/03\/line_green3_left.png\" background_size=\"custom\" background_image_height=\"600px\" background_position=\"top_left\" background_vertical_offset=\"0%\" custom_margin=\"-390px|0px|0px||false|false\" custom_padding=\"|0px|0px|0px|false|false\" custom_css_free_form=\"selector{|| width:740px;|| height:390px;|| top:auto;bottom:-120px;|| left:auto;right:-15px;|| z-index:0;||}\" global_colors_info=\"{}\"][et_pb_column type=\"4_4\" _builder_version=\"4.24.2\" _module_preset=\"default\" global_colors_info=\"{}\"][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" _builder_version=\"4.24.2\" _module_preset=\"default\" global_colors_info=\"{}\"][et_pb_row _builder_version=\"4.24.2\" _module_preset=\"default\" global_colors_info=\"{}\"][et_pb_column type=\"4_4\" _builder_version=\"4.24.2\" _module_preset=\"default\" global_colors_info=\"{}\"][et_pb_text _builder_version=\"4.27.4\" _module_preset=\"default\" text_text_color=\"gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2\" text_font_size=\"16px\" link_text_color=\"gcid-4aeecbf4-ad8a-42cd-966b-141db4843095\" custom_padding=\"|26px||0px|false|false\" locked=\"off\" global_colors_info=\"{%22gcid-07fd6007-ae25-4e13-bbf0-52acc155a8b2%22:%91%22text_text_color%22%93,%22gcid-4aeecbf4-ad8a-42cd-966b-141db4843095%22:%91%22link_text_color%22%93}\"]\n<p style=\"font-weight: 400;\"><strong>Vos conditions de travail :<\/strong><\/p>\nAu sein de l\u2019un de notre site de Lyon, vous \u00eates accueilli dans une ambiance conviviale et bienveillante, dans laquelle chaque membre de l\u2019\u00e9quipe participe \u00e0 une atmosph\u00e8re de travail privil\u00e9giant l\u2019entraide, favorisant la cr\u00e9ativit\u00e9 et g\u00e9n\u00e9rant ainsi l\u2019am\u00e9lioration continue des comp\u00e9tences et de la performance au service de la satisfaction de nos clients.\n\nVotre r\u00e9mun\u00e9ration est fix\u00e9e en fonction de votre exp\u00e9rience et vous b\u00e9n\u00e9ficiez des avantages suivants\u00a0: Mutuelle obligatoire, Tickets restaurants \u00e0 10 euros, Accord d\u2019int\u00e9ressement et Plan d\u2019\u00e9pargne inter-entreprises, forfait mobilit\u00e9 durable.\n\nMerci d'envoyer votre dossier de candidature (CV+ lettre de motivation) \u00e0 <a href=\"mailto:aurelie.schmidt@heva-data.com\">benjamin.grenier@heva-data.com<\/a>.\n\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]","_et_gb_content_width":"","advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[6],"tags":[],"class_list":["post-6058","post","type-post","status-publish","format-standard","hentry","category-offre-demploi"],"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/pgrg3B-1zI","_links":{"self":[{"href":"https:\/\/heva-data.com\/en\/wp-json\/wp\/v2\/posts\/6058","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/heva-data.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/heva-data.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/heva-data.com\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/heva-data.com\/en\/wp-json\/wp\/v2\/comments?post=6058"}],"version-history":[{"count":22,"href":"https:\/\/heva-data.com\/en\/wp-json\/wp\/v2\/posts\/6058\/revisions"}],"predecessor-version":[{"id":6284,"href":"https:\/\/heva-data.com\/en\/wp-json\/wp\/v2\/posts\/6058\/revisions\/6284"}],"wp:attachment":[{"href":"https:\/\/heva-data.com\/en\/wp-json\/wp\/v2\/media?parent=6058"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/heva-data.com\/en\/wp-json\/wp\/v2\/categories?post=6058"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/heva-data.com\/en\/wp-json\/wp\/v2\/tags?post=6058"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}